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A study on the association of the chromosome 12p13 locus with sporadic late-onset Alzheimer's disease in Chinese

✍ Scribed by Song, You-Qiang; Li, Yan; Chu, Leung Wing; Yik, Ping-Yiu

Book ID
122449298
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
51 KB
Volume
5
Category
Article
ISSN
1552-5260

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## Abstract The __MAPT__ gene that encodes Tau is located on chromosome 17q21, in a region, which has evolved to form two major haplotypes, H1 and H2. There is strong evidence that the H1 haplotype, and a sub‐haplotype (H1C), are overrepresented and associated with increased risk for the sporadic t