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A study of the in vitro interaction between lidocaine and premedications using human liver microsomes

✍ Scribed by A. Nagashima; E. Tanaka; S. Inomata; K. Honda; S. Misawa


Book ID
108848828
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
107 KB
Volume
30
Category
Article
ISSN
0269-4727

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Structure elucidation of aplidine metabo
✍ Esther F. A. Brandon; Ronald D. van Ooijen; Rolf W. Sparidans; Luis LΓ³pez LΓ‘zaro πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 467 KB

## Abstract The cyclic depsipeptide aplidine is a new anti‐cancer drug of marine origin. Four metabolites of this compound were found after incubation with pooled human microsomes using gradient high‐performance liquid chromatography with ultraviolet detection. After chromatographic isolation, the