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A study of the hydration of ribonuclease A using densitometry: Effect of the protein hydrophobicity and polarity

โœ Scribed by Sirotkin, Vladimir A.; Khadiullina, Aigul V.


Book ID
122267373
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
806 KB
Volume
603
Category
Article
ISSN
0009-2614

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## Abstract Enzymes with ribonucleolytic activity play a pivotal role in gene expression and cellular homeostasis by altering the levels of cellular RNA. Ribonuclease A has been the most well studied of such enzymes whose histidine residues (His^12^ and His^119^) play a crucial role in the catalyti