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A Study of the Conformation of HIV Nef Bound to Lipid Membranes by Neutron Reflectivity

✍ Scribed by Kent, Michael S.; Murton, Jaclyn K.; Satija, Sushil; Akgun, Bulent; Nanda, Hirsh; Curtis, Joseph; Majewski, Jaroslaw; Morgan, Christopher; Engen, John R.

Book ID
122302132
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
40 KB
Volume
98
Category
Article
ISSN
0006-3495

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## Abstract The monotopic proteins COX‐1 and ‐2 in dimeric form bound to lipid bilayer membranes are studied using molecular dynamics simulations within an aqueous environment. The 25‐ns simulations are performed for both isozymes with arachidonic acid bound in the cyclooxygenase sites. The interac