A study of riluzole in the treatment of advanced stage or elderly patients with amyotrophic lateral sclerosis
β Scribed by G. Bensimon; L. Lacomblez; J. C. Delumeau; R. Bejuit; P. Truffinet; V. Meininger; for the Riluzole/ALS Study Group III
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 261 KB
- Volume
- 249
- Category
- Article
- ISSN
- 0340-5354
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π SIMILAR VOLUMES
Maximal voluntary isometric contraction (MVIC) is becoming widely used for monitoring disease progression in amyotrophic lateral sclerosis (ALS). We evaluated the variability of MVIC in a large multicenter (29 sites) drug trial in ALS. Intra-and interrater variability were assessed twice during the
## Abstract Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the progressive and simultaneous degeneration of upper and lower motor neurons. The pathological process associated to ALS, albeit more pronounced in the motor/premotor cortices and along the corticospin