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A study of prolyl endopeptidase in bovine serum and its relevance to the tissue enzyme

✍ Scribed by Damian F. Cunningham; Brendan O'Connor


Book ID
117756368
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
363 KB
Volume
30
Category
Article
ISSN
1357-2725

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## Abstract The enzyme specificity and tissue distribution of zenarestat, an aldose reductase inhibitor, was investigated in diabetic rats. Zenarestat inhibited both rat sciatic nerve aldose reductase (AR) activity and recombinant human AR with IC~50~ values of 7.5 and 44 nM, respectively. However,