## Abstract Metabolic activation of drug candidates to electrophilic reactive metabolites that can covalently modify cellular macromolecules may result in acute and/or idiosyncratic immune systemβmediated toxicities in humans. This presents a significant potential liability for the future developme
A study of fatigue crack closure using electric potential and compliance techniques
β Scribed by C.K. Clarke; G.C. Cassatt
- Publisher
- Elsevier Science
- Year
- 1977
- Tongue
- English
- Weight
- 909 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0013-7944
No coin nor oath required. For personal study only.
β¦ Synopsis
The objective of this study was to compare closure data obtained on the same specimen with crack tip compliance gage and electric potential techniques. Equivalent results on closure using the two techniques were obtained on 7075-T651 aluminum center cracked panels. The results also indicated that closure was a function of stress ratio, specimen thickness and maximum applied stress intensity. Maximum stress intensity had a particularly strong effect on closure in the range of applied stresses used. This observed dependence of closure on specimen thickness and maximum stress intensity should account for many of the discrepancies in closure behavior found in the literature. Observations on potential system behavior during closure measurements are also reported.
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