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A study of biases of DNA copy number estimation based on PICR model

✍ Scribed by Quan Wang; Jianghan Qu; Xiaoxing Cheng; Yongjian Kang; Lin Wan; Minping Qian; Minghua Deng

Book ID
107378056
Publisher
Higher Education Press and Springer
Year
2011
Tongue
English
Weight
971 KB
Volume
6
Category
Article
ISSN
1673-3452

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## Abstract Activation of oncogenic __Kras__ in murine lung leads to the development of numerous small adenomas, only some of which progress over time to overt adenocarcinoma. Thus, although __Kras__ is the initiating oncogene, it is likely that secondary genetic events are required for progression