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A study of aspartyl proteases using intramolecularly quenched fluorogenic peptide substrates

✍ Scribed by I. Yu. Filippova; E. N. Lysogorskaya; G. I. Lavrenova; E. S. Oksenoit; L. I. Suvorov; V. V. Starovoitova


Book ID
105608285
Publisher
SP MAIK Nauka/Interperiodica
Year
2000
Tongue
English
Weight
452 KB
Volume
26
Category
Article
ISSN
1068-1620

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Two series of intramolecularly quenched fluorogenic oligopeptide substrates with the general sequences DABCYL-Lys-Phe-GIy-GIy-AIa-Xxx-EDANS and Abz-Lys-Phe-Gly-Gly-Ala-Xxx-Tyr(m-NO2)-NH 2 have been used to explore the effect of P3' substituents and donor/acceptor pairs on the kinetic parameters for