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A Structure for the Trimeric MHC Class II-associated Invariant Chain Transmembrane Domain

โœ Scribed by Andreas Kukol; Jaume Torres; Isaiah T Arkin

Book ID
117142901
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
371 KB
Volume
320
Category
Article
ISSN
0022-2836

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Proteolysis of the invariant chain (li) leads to the generation of abundant MHC class II-associated invariant chain peptides (CLIP), which bind in the MHC class II binding groove via supermotifs in a manner similar to that of antigenic peptides. We have engineered an li vector with the capacity to e