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A Structure-Based Model for the Synthesis and Hydrolysis of ATP by F1-ATPase

✍ Scribed by Yi Qin Gao; Wei Yang; Martin Karplus

Book ID
116352819
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
433 KB
Volume
123
Category
Article
ISSN
0092-8674

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Hydrolysis and synthesis of ATP by membr
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ATPase was detected in the membranes of a motile Streptococcus. Maximal enzymic activity was observed at pH 8 and ATP/Mg 2 Β§ ratio of 2. Mn 2 + and Ca 2 Β§ could replace Mg 2 + to some extent. Besides ATP, GTP and ITP were substrates. The enzyme was inhibited by N,N'-dicyclohexylcarbodiimide but not