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A Structural View of Integrin Activation and Signaling

โœ Scribed by Filippo G. Giancotti

Book ID
117795327
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
78 KB
Volume
4
Category
Article
ISSN
1534-5807

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Integrins are cell adhesion receptors that transmit bidirectional signals across plasma membrane and are crucial for many biological functions. Recent structural studies of integrin transmembrane (TM) and cytoplasmic domains have shed light on their conformational changes during integrin activation.