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A Structural Determinant of Desensitization and Allosteric Regulation by Pentobarbitone of the GABAAReceptor

✍ Scribed by B. Birnir; M.L. Tierney; J.E. Dalziel; G.B. Cox; P.W. Gage


Publisher
Springer
Year
1997
Tongue
English
Weight
206 KB
Volume
155
Category
Article
ISSN
0022-2631

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An acyclic glycol ether ligand with two nitroxide groups shows in frozen solution a dipole-dipole interaction only in the presence of potassnun ions. Al TOOT temperature the spin-spin exchange is still observed, but it is amplified in presence of K+, The results UC discussed in terms af conformation