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A Structural and Functional Model of Galactose Oxidase: Control of the One-Electron Oxidized Active Form through Two Differentiated Phenolic Arms in a Tripodal Ligand

✍ Scribed by Fabrice Thomas; Gisèle Gellon; Isabelle Gautier-Luneau; Eric Saint-Aman; Jean-Louis Pierre


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
100 KB
Volume
114
Category
Article
ISSN
0044-8249

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A Structural and Functional Model of Gal
✍ Fabrice Thomas; Gisèle Gellon; Isabelle Gautier-Luneau; Eric Saint-Aman; Jean-Lo 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 100 KB 👁 2 views

Galactose oxidase (GOase) is a type II copper protein (68 kDa) that catalyzes the oxidation of primary alcohols to aldehydes with the concomitant reduction of molecular oxygen. [1] Its crystal structure [2] reveals a unique mononuclear copper site with two nitrogen (from histidine imidazole groups)