A strategy with label-free quantification of the targeted peptides for quantitative peptidome analysis of human serum

Targeting AKT with the proapoptotic pept

Targeting AKT with the proapoptotic peptide, TAT-CTMP: A novel strategy for the treatment of human pancreatic adenocarcinoma

✍ Peter O. Simon Jr.; Jonathan E. McDunn; Hiroyuki Kashiwagi; Katherine Chang; Pet 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 695 KB

## Abstract Pancreatic adenocarcinoma carries an ominous prognosis and has little effective treatment. Several studies have demonstrated that the potently antiapoptotic phosphatidyl inositol 3′‐kinase (PI3K)—protein kinase B/AKT pathway is active in pancreas cancer. A recent study identified an end