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A Strategy to Detect and Isolate an Intron-Containing Gene in the Presence of Multiple Processed Pseudogenes

✍ Scribed by Brendan Davies, Salvatore Feo, Edith Heard and Mike Fried


Book ID
123637284
Publisher
National Academy of Sciences
Year
1989
Tongue
English
Weight
890 KB
Volume
86
Category
Article
ISSN
0027-8424

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A processed pseudogene of the rat HscTO gene, HscTOpsl, is described, which still presents the open reading frame of the original gene. The pseudogene does not appear to be expressed. It maps to rat Chromosome (Chr) 2. The intron-carrying Hsc70 gene localizes to Chr 8. Hsc70-specific probes detect a