A Straightforward, Highly Stereoselectiv
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Patricia Castejón; Albert Moyano; Miquel A. Pericàs; Antoni Riera
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Article
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1996
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John Wiley and Sons
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English
⚖ 795 KB
A novel strategy for the synthesis of isostatine derivatives has been developed. Contrary to previous approaches to isostatine, a non-proteinogenic amino acid that is an essential component of the didemnins, the present synthesis does not require the intermediacy of the expensive amino acid D-do-iso