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A Stereospecific Synthesis of Alicyclic and Bicyclic Amines via Hydroboration

โœ Scribed by Rathke, Michael W.; Inoue, Naoto; Varma, K. R.; Brown, Herbert C.


Book ID
111904320
Publisher
American Chemical Society
Year
1966
Tongue
English
Weight
264 KB
Volume
88
Category
Article
ISSN
0002-7863

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Michael addition of beterocyclic amines (6). (lo), ( 13) and ( 17) to nilro-olefm (3) followed by feductionkyclization of the ~&XI group of the adduct provides a convenient synthesis of the bicyclic pytazinones 0%. ( 12). ( 16). ( 19) and ( 20) which are found in several natmal pfoducts.