ChemInform Abstract: A Stereoselective S
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Simon J. F. Macdonald; Keith Mills; Julie E. Spooner; Richard J. Upton; Michael
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Article
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2010
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John Wiley and Sons
⚖ 32 KB
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A Stereoselective Synthesis via a 5-exo-trig Cyclization of trans-2-Oxohexahydro-2H-furo[3,2-b]pyrroles (Pyrrolidine-trans-lactones) -Potent, Novel Elastase Inhibitors. -With the title cyclization to (VI) as the key step, a stereoselective approach to a potent human neutrophile elastase inhibitor (