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A stereoselective synthesis of α-halo vinyl sulfides and their applications in organic synthesis

✍ Scribed by Mei Su; Wensheng Yu; Zhendong Jin


Book ID
104230622
Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
123 KB
Volume
42
Category
Article
ISSN
0040-4039

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Lanthanum oxide/TMEDA-catalyzed cross-coupling of vinyl halides with thiols/diphenyl diselenide in anhydrous DMSO and KOH is reported. Utilizing this protocol various vinyl sulfides and selenides were synthesized in excellent yields with retention of the stereochemistry. The catalyst was recyclable.