We report here an efficient one-pot diastereoselective procedure which transforms silylated vinyloxiranes 2 into enantiomerically pure tetrasubstituted d-lactones 7, 10. This transformation includes four steps: palladium(0)-catalyzed rearrangement/alkylation-lactonization/1,4-conjugated addition/ele
A Stereoselective Synthesis of Silylated Epoxycyclopentanols Bearing four Contiguous Stereogenic Centers.
β Scribed by Serge Thorimbert; Catherine Taillier; Sebastian Bareyt; Delphine Humiliere; Max Malacria
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 25 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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