✦ LIBER ✦
A stereoselective one-pot synthesis of perhydro-7a-hydroxy-7-phenylthiofurano[3,2-b]pyran via an Acid-catalysed deprotection/double cyclisation/rearrangement sequence
✍ Scribed by Neil Edwards; Jacqueline A. Macritchie; Philip J. Parsons
- Book ID
- 104259194
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 186 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Treatment of 1,3-bis-[(tert-butyldimethylsilyloxy)ethyl]-1-phenylsulfinyl-1,2-propadiene with aqueous I-IF in acetonitrile :ed to the formation of the rifle compound as one diastereoisomer (from NMR analysis). The reaction was carried out under thermodynamic conditions, and underwent a double deprotection/double cyclisation/rearrangement sequence.