A stereodivergent synthesis of 3,4-disubstituted-2-azetidinones
β Scribed by Maree P. Collis; Patrick Perlmutter
- Book ID
- 108036462
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 919 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0957-4166
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π SIMILAR VOLUMES
Chiral 5,6-disubstituted-5,6-dihydro-2(1H)-pyridones were prepared efficiently from readily accessible 3,4-disubstituted-2-azetidinones having preadjusted substituents and stereochemistry through the reductive ring opening of 2-azetidinones followed by Z-selective installation of acetate moiety and
## A Stereodivergent Synthesis of Chiral 4,5-Disubstituted Bis(Oxazolines) . -Following the cyclization procedures shown in the scheme, two different types of ligands (IV) and (V) can be prepared with retention or inversion starting from the same diamides (III). -(DESIMONI,
A short chemical process is described for the synthesis of optically active 3y roxy-4-alkoxycarbonyl-Z-azetidinones (R-lactams) from L-tartaric acid. Tartaric acid is an extremely useful and versatile member of the chiral pool. Since nearly any type of f+hydroxy acid can be converted to a 8-lactam (