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A Statistical Kinetic Model for the Bulk Degradation of PLA- b -PEG- b -PLA Hydrogel Networks

✍ Scribed by Metters, Andrew T.; Bowman, Christopher N.; Anseth, Kristi S.

Book ID
126844234
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
81 KB
Volume
104
Category
Article
ISSN
0022-3654

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A Statistical Kinetic Model for the Bulk
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✍ Metters, Andrew T.; Bowman, Christopher N.; Anseth, Kristi S. πŸ“‚ Article πŸ“… 2000 πŸ› American Chemical Society 🌐 English βš– 81 KB

A theoretical model has been developed to describe the bulk-degradation behavior of model PEG-b-PLA hydrogels. Utilizing a statistical approach to predict the cleavage of cross-links within these networks, the model accounts for both structural and kinetic issues during the degradation and, from dir

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✍ Andrew T. Metters; Christopher N. Bowman; Kristi S. Anseth πŸ“‚ Article πŸ“… 2001 πŸ› American Institute of Chemical Engineers 🌐 English βš– 113 KB

## Abstract Several macroscopic properties of degrading poly(lactic acid)‐b‐poly(ethylene glycol)‐b‐poly(lactic acid) (PLA‐b‐PEG‐b‐PLA) hydrogels were compared to one another as functions of degradation time. The specific hydrogel properties measured were the compressive modulus (K), the volumetric