A statistical analytical approach to predict the secondary structure of proteins from amino acid sequence information
β Scribed by Shrish Tiwari; Boojala V. B. Reddy
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 160 KB
- Volume
- 101
- Category
- Article
- ISSN
- 1432-2234
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The multidimensional statistical technique of discriminant analysis is used to allocate amino acid sequences to one of four secondary structural classes: high a content, high / 3 content, mixed a and @, low content of ordered structure. Discrimination is based on four attributes: estimates of percen
## Abstract To improve secondary structure predictions in protein sequences, the information residing in multiple sequence alignments of substituted but structurally related proteins is exploited. A database comprised of 70 protein families and a total of 2, 500 sequences, some of which were aligne