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A standardized method of using nude mice for the in vivo screening of antitumor drugs for human tumors

โœ Scribed by Munehisa Imaizumi; Tatsuhei Kondo; Tetsuo Taguchi; Takao Hattori; Osahiko Abe; Morimasa Kitano; Akira Wakui

Book ID
112289966
Publisher
Springer
Year
1993
Tongue
English
Weight
707 KB
Volume
23
Category
Article
ISSN
1436-2813

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## Abstract Our previous studies demonstrated that the oral antifungal agent ketoconazole (KT) induces apoptosis and G0/G1 phase cell cycle arrest in human cancer cell lines. In this study, we first demonstrated that KT (1 ฮผM) potentiated the apoptotic effects of nocodazole (ND, 1 nM) in COLO 205 c