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A stable analogue of glucose-dependent insulinotropic polypeptide, GIP(LysPAL16), enhances functional differentiation of mouse embryonic stem cells into cells expressing islet-specific genes and hormones

โœ Scribed by Marenah, Lamin; McCluskey, Jane T.; Abdel-Wahab, Yasser H.A.; O'Harte, Finbarr P.M.; McClenaghan, Neville H.; Flatt, Peter R.


Book ID
121254521
Publisher
Walter de Gruyter GmbH & Co. KG
Year
2006
Tongue
English
Weight
178 KB
Volume
387
Category
Article
ISSN
1431-6730

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A stable analogue of glucose-dependent i
โœ Marenah, Lamin; McCluskey, Jane T.; Abdel-Wahab, Yasser H.A.; O'Harte, Finbarr P ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› Walter de Gruyter GmbH & Co. KG ๐ŸŒ English โš– 178 KB

Embryonic stem (ES) cells can be differentiated into insulin-producing cells by conditioning the culture media. However, the number of insulin-expressing cells and amount of insulin released is very low. Glucose-dependent insulinotropic polypeptide (GIP) enhances the growth and differentiation of pa