A stabilized molten globule protein
β Scribed by Jui-Yoa Chang; Alexey Bulychev; Li Li
- Book ID
- 117102571
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 156 KB
- Volume
- 487
- Category
- Article
- ISSN
- 0014-5793
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Nereis sarcoplasmic Ca 2Ψ -binding protein (NSCP) is a calcium buffer protein that binds Ca 2Ψ ions with high affinity but is also able to bind Mg 2Ψ ions with high positive cooperativity. We investigated the conformational and stability changes induced by the two metal ions. The thermal reversible
The background to the concept of the term "molten globule" as a description of intermediates observed in the folding of globular proteins is discussed. These compact intermediates are characterised by certain properties including the presence of secondary structure and considerable conformational mo