## Abstract DNAโdependent protein kinase (DNAโPK), a nuclear serine/threonine kinase, is responsible for the DNA doubleโstrand break repair. Cells lacking or with dysfunctional DNAโPK are often associated with misโrepair, chromosome aberrations, and complex exchanges, all of which are known to cont
โฆ LIBER โฆ
A sphingosine kinase inhibitor induces cell death in temozolomide resistant glioblastoma cells
โ Scribed by Meryem Bektas; Stewart P. Johnson; William E. Poe; Darell D. Bigner; Henry S. Friedman
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 327 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0344-5704
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## Abstract Parkinson's disease is a neurodegenerative disorder associated with the selective death of dopaminergic neurons. Glial cell lineโderived neurotrophic factor (GDNF) can protect dopaminergic neurons in several parkinsonian models. We used the dopaminergic cell line MN9D to explore the mec
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