Combined applications of affinity purification procedures and mass-spectrometric analyses (affinity mass spectrometry or affinity-directed mass spectrometry) have gained broad interest in various fields of biological sciences. We have extended these techniques to the purification and analysis of clo
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A Spherical Polar Fourier correlations-based approach for prediction of the effect of ligands on protein–protein interactions
✍ Scribed by Hanif Vahedian-Movahed; Mohmmad-Reza Saberi; Jamshid Chamani
- Book ID
- 118430713
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 60 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0009-9120
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## Abstract Enzymes with ribonucleolytic activity play a pivotal role in gene expression and cellular homeostasis by altering the levels of cellular RNA. Ribonuclease A has been the most well studied of such enzymes whose histidine residues (His^12^ and His^119^) play a crucial role in the catalyti