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A Sperm Cytoskeletal Protein That Signals Oocyte Meiotic Maturation and Ovulation

✍ Scribed by Miller, M. A.

Book ID: 115498754
Publisher: American Association for the Advancement of Science
Year: 2001
Tongue: English
Weight: 589 KB
Volume: 291
Category: Article
ISSN: 0036-8075
DOI: 10.1126/science.1057586

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## Abstract Accumulating evidence has indicated that vertebrate oocytes are arrested at late prophase (G2 arrest) by a G protein coupled receptor (GpCR) that activates adenylyl cyclases. However, the identity of this GpCR or its regulation in G2 oocytes is unknown. We demonstrated that ritanserin (