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A speculation on the pathogenesis of joint inflammation in rheumatoid arthritis

✍ Scribed by Nathan J. Zvaifler

Publisher
John Wiley and Sons
Year
1965
Tongue
English
Weight
313 KB
Volume
8
Category
Article
ISSN
0004-3591

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✦ Synopsis

URING THE PAST FEW YEARS there has been a renewal of interest D in the study of synovial fluid. One recent development has been the demonstration of unusual inclusion bodies within the leukocytes present in inflammatory effusions. While not exclusively limited to rheumatoid arthritis, the phenomenon appears to be most frequent and pronounced in this disease.

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✍ Xiaobo Wu; Fei Shih; John P. Atkinson πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 102 KB πŸ‘ 1 views

In our ongoing efforts to explain the immunopathogenesis of rheumatoid arthritis (RA), we will integrate and highlight two recent advances. The first advance is the identification of IgG autoantibodies to citrullinated peptides in a substantial (30-50%) portion of patients with RA and their role as