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A spectroscopic study of the photobleaching of protoporphyrin IX in solution

✍ Scribed by M. B. Ericson; S. Grapengiesser; F. Gudmundson; A-M. Wennberg; O. Larkö; J. Moan; A. Rosén

Book ID
106274317
Publisher
Springer-Verlag
Year
2003
Tongue
English
Weight
458 KB
Volume
18
Category
Article
ISSN
0268-8921

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✍ Johan Moan; Giedre Streckyte; Saulius Bagdonas; Øystein Bech; Kristian Berg 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 208 KB 👁 2 views

Protoporphyrin IX (Pp IX) is the main photosensitizer in photochemotherapy with 5-aminolevulinic acid (ALA). Pp IX is photolabile and the present work shows that 70-95% of Pp IX in cells is degraded by clinically relevant light exposures (40-200 J cm 22 at 630 nm). During light exposure a small yiel