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A SPECIFIC ORALLY ACTIVE INHIBITOR OF ANGIOTENSIN-CONVERTING ENZYME IN MAN

✍ Scribed by Ferguson, RogerK; Brunner, HansR; Turini, GustaveA; Gavras, Haralambos; Mckinstry, DorisN


Book ID
121947979
Publisher
The Lancet
Year
1977
Tongue
English
Weight
542 KB
Volume
309
Category
Article
ISSN
0140-6736

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The disposition characteristics of pentopril (the ethyl ester) and its active carboxylic acid metabolite (CGS 13934) were determined in conscious rats after separate intravenous administrations of both compounds. The relationship between plasma concentration and pharmacological effect was also evalu