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A specific acylating agent for the [3H]phencyclidine receptors in rat brain

✍ Scribed by Michael F. Rafferty; Mariena Mattson; Arthur E. Jacobson; Kenner C. Rice

Book ID
115916683
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
483 KB
Volume
181
Category
Article
ISSN
0014-5793

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✍ T. Maurice; J. Vignon πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 774 KB

The phencyclidine (PCP) derivative N-[l-(2-thienyl) cyclohexyl]-piperidine (3H-TCP) was used to label in vivo the N-methyl-D-aspartate (NMDA) receptor-associated ionic channel in the mouse brain. After the injection of a tracer dose of 3H-TCP, a spread labeling throughout the brain was observed, but