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A soluble form of CD83 is released from activated dendritic cells and B lymphocytes, and is detectable in normal human sera

✍ Scribed by Hock, B. D.

Book ID
124071754
Publisher
Oxford University Press
Year
2001
Tongue
English
Weight
242 KB
Volume
13
Category
Article
ISSN
0953-8178

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CD137 (ILA/4-1BB) is a member of the tumor necrosis factor receptor family and regulates activation, proliferation and programmed cell death in T lymphocytes. Here we show the existence of a soluble form of CD137 (sCD137) of 16 kDa. sCD137 is released by activated lymphocytes, and in contrast to mem