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A solid-state proton NMR investigation of amino acids found in proteins

✍ Scribed by E.R. Andrew; W.S. Hinshaw; M.G. Hutchins; P.C. Canepa

Publisher: Elsevier Science
Year: 1974
Tongue: English
Weight: 253 KB
Volume: 26
Category: Article
ISSN: 0009-2614
DOI: 10.1016/0009-2614(74)89080-9

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✦ Synopsis

A proton NMR relaxation study has been carried out in the solid state on ten of the twenty animo acids encotmtered in proteins, namely alanine, arginine, aspartic acid, glutamine. glycine, isoleucine, leucine, methionine, serine and wline. In all cams a refa.xz&x~ minimum attributed to reorientation of the NH3 group was found, with activation energies from 29 to 50 kJ/moIe. Additional minima were observed at lower temperatures in amino acids with methyl groups, whose reorientation'was characterized by activation energies from 12 to 21 kJ/mole_

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