A novel, mild method for the synthesis of di-and trisubstituted N-acyl ureas on solid support is described. Addition of carboxylic acids to a resin-bound carbimidoyl chloride gave, initially, an O-acyl isourea which subsequently rearranged to the corresponding N-acyl urea. Trisubstituted N-acyl urea
✦ LIBER ✦
A Solid-Phase Synthesis of N,N‘-Disubstituted Ureas and Perhydroimidazo[1,5- a ]pyrazines via the Curtius Rearrangement
✍ Scribed by Migawa, Michael T.; Swayze, Eric E.
- Book ID
- 119961868
- Publisher
- American Chemical Society
- Year
- 2000
- Tongue
- English
- Weight
- 148 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1523-7060
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
A novel solid-phase synthesis of di- and
✍
Jacob Ravn; Michael Ankersen; Mikael Begtrup; Jesper F. Lau
📂
Article
📅
2003
🏛
Elsevier Science
🌐
French
⚖ 376 KB
ChemInform Abstract: Synthesis of N,N-Di
✍
Ina Wilkening; Giuseppe del Signore; Christian P. R. Hackenberger
📂
Article
📅
2008
🏛
John Wiley and Sons
⚖ 27 KB
👁 2 views
A practical synthesis of enantiopure N-c
✍
Jun-ichi Matsuo; Masahiko Okano; Kosuke Takeuchi; Hiroyuki Tanaka; Hiroyuki Ishi
📂
Article
📅
2007
🏛
Elsevier Science
🌐
English
⚖ 145 KB
A convenient solution and solid-phase sy
✍
Jie-Fei Cheng; Mi Chen; Thomas Arrhenius; Alex Nadzan
📂
Article
📅
2002
🏛
Elsevier Science
🌐
French
⚖ 95 KB
An extremely efficient synthesis of D 5 -2-oxopiperazines in solution phase and on solid support has been established via a Ugi four-component condensation reaction (U-4CC) followed by N-acyliminium ion cyclization between the aldehyde (acetal) functionality and the newly formed amide bond. The desi
A Convenient Solution and Solid-Phase Sy
✍
Jie-Fei Cheng; Mi Chen; Thomas Arrhenius; Alex Nadzan
📂
Article
📅
2010
🏛
John Wiley and Sons
⚖ 30 KB
👁 1 views
Efficient synthesis of 1,4-disubstituted
✍
Pal, Rammyani; Sarkar, Swarbhanu; Chatterjee, Nivedita; Sen, Asish Kumar
📂
Article
📅
2013
🏛
Elsevier Science
🌐
French
⚖ 560 KB