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A sodium channel defect in hyperkalemic periodic paralysis: Potassium-induced failure of inactivation

โœ Scribed by Cannon, Stephen C.; H. Brown, Robert; Corey, David P.


Book ID
122779609
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
901 KB
Volume
6
Category
Article
ISSN
0896-6273

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Hyperkalemic periodic paralysis (HPP) is caused by mutations of the adult skeletal muscle sodium channel (SCN4A) gene on chromosome 17. Malignant hyperthermia (MH) is a genetically heterogeneous autosomal-dominant disorder occurring in association with various neuromuscular diseases or without other