A thin-layer gas-solution microcalorimeter has been developed to study the binding reactions of gaseous ligands with ligand binding macromolecules in solution. Gas partial pressures are accurately changed logarithmically by means of a precision dilution valve allowing for the stepwise determination
A small volume microcalorimeter for analytical determinations
β Scribed by Sam N. Pennington
- Publisher
- Elsevier Science
- Year
- 1976
- Tongue
- English
- Weight
- 402 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0003-2697
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β¦ Synopsis
A new design in microcaIorimeters utilizing a unique detector configuration that gives good sensitivity and rapid analysis time is described. The detector is capable of sensing less than 5 meal without additional amplification and uses only small (lo-100 ~1) volumes of sample. Application to several inorganic, organic, and biochemical reactions are given. The advantages of heat-sensing instrumentation with respect to analytical determinations are augmented by the rapidity of operation of the described instrumentation. 230
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