A small supernumerary marker chromosome X identified by in situ hybridization
✍ Scribed by Asli N. Silahtaroglu; Seniha Hacihanefioglu; Sükriye Yilmaz; Yelda Tarkan; Asim Cenani; Zeynep Tümer
- Book ID
- 115091773
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 737 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0009-9163
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We present a patient with multiple anomalies and severe developmental delay. A small supernumerary ring chromosome was found in 40% of her lymphocyte cells at birth. The origin of the marker chromosome could not be determined by GTG banding, but fluorescent in situ hybridization (FISH) later identif
A father and his 2 daughters were previously determined to carry a small, supernumerary marker chromosome [Chudley et al., 1983]. The origin of this marker could not be determined by standard cytogenetic techniques. In this study, fluorescence in situ hybridization (FISH) studies identified the mark