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A small dose of the immunosuppressive agent FK506 (tacrolimus) protects peripheral nerve from ischemic fiber degeneration

โœ Scribed by Mikihiro Kihara; Mikiko Kamijo; Yoshikuni Nakasaka; Yoshiyuki Mitsui; Mitsuo Takahashi; James D. Schmelzer


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
475 KB
Volume
24
Category
Article
ISSN
0148-639X

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โœ Mikihiro Kihara; James D. Schmelzer; Yoriko Kihara; Inge L. Smithson; Phillip A. ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 768 KB

Since peripheral nerve has a large ischemic safety factor, hypothermia, by reducing metabolic demands, is potentially an efficacious technique to rescue nerve from ischemic fiber degeneration (IFD). We therefore evaluated the influence of temperature on the severity of IFD resulting from a standard