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A Single Residue Influences the Reaction Mechanism of Ammonia Lyases and Mutases

✍ Scribed by Sebastian Bartsch; Uwe T. Bornscheuer


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
631 KB
Volume
48
Category
Article
ISSN
0044-8249

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## Abstract In the present DFT study, the catalytic mechanism of H~2~O~2~ formation in the oxidative half‐reaction of NiSOD, E‐Ni(II) + O + 2H^+^ → E‐Ni(III) + H~2~O~2~, has been investigated. The main objective of this study is to investigate the source of two protons required in this half‐reactio