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A single-pool inositol 1,4,5-trisphosphate-receptor-based model for agonist-stimulated oscillations in Ca2+ concentration.

✍ Scribed by De Young, G. W.; Keizer, J.


Book ID
124056881
Publisher
National Academy of Sciences
Year
1992
Tongue
English
Weight
906 KB
Volume
89
Category
Article
ISSN
0027-8424

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We investigate the various types of complex Ca 2+ oscillations which can arise in a model based on the mechanism of Ca 2+ -induced Ca 2+ release (CICR), that takes into account the Ca 2+ -stimulated degradation of inositol 1,4,5-trisphosphate (InsP 3 ) by a 3-kinase. This model was previously propos