A single peptide derived from the sequence common to polyoma small and middle t-antigen induces immunity against polyoma tumors

Immunization against polyoma tumors with

Immunization against polyoma tumors with synthetic peptides derived from the sequences of middle-and large-T antigens

✍ Git Reinholdsson-Ljunggren; Torbjörn Ramqvist; Lars Ährlund-Richter; Tina Dalian 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 French ⚖ 576 KB

We have used 9 synthetic peptides corresponding to sequences of polyoma virus small-T, middle-T and large-T antigens as immunogens in order to map antigenic epitopes that can induce polyoma-tumor-specific immunity in different mouse strains. We found that immunization of mice with synthetic peptides