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A single-nucleotide polymorphism tagging set for human drug metabolism and transport

โœ Scribed by Ahmadi, Kourosh R; Weale, Mike E; Xue, Zhengyu Y; Soranzo, Nicole; Yarnall, David P; Briley, James D; Maruyama, Yuka; Kobayashi, Mikiro; Wood, Nicholas W; Spurr, Nigel K; Burns, Daniel K; Roses, Allen D; Saunders, Ann M; Goldstein, David B


Book ID
109919094
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
303 KB
Volume
37
Category
Article
ISSN
1061-4036

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Single nucleotide polymorphisms (SNPs) play a central role in the identification of susceptibility genes for common diseases. Recent empirical studies on human genome have revealed block-like structures, and each block contains a set of haplotype tagging SNPs (htSNPs) that capture a large fraction o