A single-nucleotide polymorphism of the TNFAIP3 gene is associated with systemic lupus erythematosus in Chinese Han population
β Scribed by Li-Qiong Cai; Zai-Xing Wang; Wen-Sheng Lu; Jian-Wen Han; Liang-Dan Sun; Wen-Hui Du; Shu-Mei Zhang; Xian-Bo Zuo; Xue-Jun Zhang; Sen Yang
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 168 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0301-4851
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## Abstract ## Objective Genomeβwide association (GWA) studies in systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) in Caucasian populations have independently identified risk variants in and near the tumor necrosis factor Ξ± (TNFΞ±)βinduced protein 3 gene (__TNFAIP3__), which is cruc
## Abstract ## Objectives/Hypothesis: The grainyheadβlike 2 gene (__GRHL2__) was found to be associated with ageβrelated hearing impairment (ARHI) in Europeans. We tested whether the same association exists in the Han Chinese population. ## Study Design: Individual cohort study. ## Methods: Am