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A single-layer peptide nanofiber for enhancing the cytotoxicity of trastuzumab (anti-HER)

✍ Scribed by Ruchi Malik, Anil Wagh, Steven Qian, Benedict Law

Book ID
120753471
Publisher
Springer Netherlands
Year
2013
Tongue
English
Weight
917 KB
Volume
15
Category
Article
ISSN
1388-0764

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Human epidermal growth factor receptor 2 (HER2) is frequently overexpressed in human breast cancers. It is known to drive tumor growth and progression and represents a prominent target in breast cancer therapy. The endothelin (ET) system, in particular ET-1 and its receptor ET A R, is of major relev