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A single gene network accurately predicts phenotypic effects of gene perturbation in Caenorhabditis elegans

โœ Scribed by Fraser, Andrew G; Marcotte, Edward M; Lee, Insuk; Lehner, Ben; Crombie, Catriona; Wong, Wendy


Book ID
109914291
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
500 KB
Volume
40
Category
Article
ISSN
1061-4036

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Predicting phenotypic effects of gene pe
โœ Karsten Borgwardt ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 57 KB

## Abstract Predicting the phenotype of an organism from its genotype is a central question in genetics. Most importantly, we would like to find out if the perturbation of a single gene may be the cause of a disease. However, our current ability to predict the phenotypic effects of perturbations of