A simulation of the effects of temperature on hippocampal neurons
โ Scribed by Michele A. Lindley; Mark P. Thomas; John M. Horowitz
- Book ID
- 113290946
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 659 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0169-2607
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The hippocampal formation, including the entorhinal cortex, the dentate gyrus, the cornu ammonis and the subiculum, plays a major role in the generation of temporal lobe epilepsy (TLE). Some forms of TLE are pharmacoresistant when treated with presently marketed drugs. These drugs have been found to
Febrile seizures are the most common seizure type in children, and hyperthermia may contribute to seizure generation during fever. We have previously demonstrated that hyperthermia suppressed g-aminobutyric acid (GABA)-ergic synaptic transmission in CA1 neurons of immature rats. However, whether thi